EU Tissue-Handling Tech

The BxChip is a patented Sectionable Matrix designed to hold biopsy core specimens throughout lab processing. Labs using the BxChip have experienced significant benefits, including:

• 14.5% average increase in histologic tissue surface area on the glass slide
• 31.8% average increase in biopsy core length
• Most notably, the overall cancer detection rate increased by 9.3%!
• 78% reduction in grossing time
• 83% reduction in embedding time
• 76% decrease in total lab time per prostate case

Options available:

• Colors: Green (left), Blue (right)
• Design: Dots and Arrows, Numbered Channels
• Lanes: 6-Lane, 12-Lane
• 16-18g core needle biopsies, 12g core needle biopsies (6-lane only)

The BxFrame is a sectionable planar matrix* made from a biomimetic organic polymer that allows the creation of tissue microarrays for routine clinical diagnostics during grossing. Tissue samples can be loaded into the site-specific receptacles of the BxFrame either in the Operating Room or the Pathology Laboratory. It ensures the preservation of spatial orientation for the tissue samples within the paraffin block and on the resulting microscope slides.

Options available: BxFrame Regular for standard cassettes; BxFrame Mega for large format cassettes; and BxFrame-p for the automated Sakura Tissue-Tek® Paraform® system. 

*The matrix material does not interfere with IHC, ISH, FISH, NGS, or other molecular testing methods. 

US PAT: 9,851,349 B2; 10,670,593 B2; 10,734,100 B2; D836,796 S; D914,238 S; 11,935,632 B2 

Lumea BxSoft Tamper is made from a silicone elastomer composite with improved thermal transfer and high latent heat. The handle is detachable and self-centering on the soft tamper (via permanent magnets).

The soft tamper is intended for flattening, aligning in the same plane, and maintaining the position of the paraffinized tissue samples when cooling the paraffin blocks on the embedding station. The tamper removes the need to apply significant force and reduces the risk of breaking fragile biological specimens.

The BxQuick Cool is a hand-held device used to cool paraffin blocks during microtomy. It’s made from a soft rubber/metal composite with improved thermal transfer.

The user can (re)cool the paraffin block to obtain serial sections without removing the block from the microtome. The surface of the paraffin block cools quickly (10-15 seconds). Lumea BxQuick Cool changes color as it cools, so you know when it’s ready – it turns blue below 1°C (the recommended temperature for maximum efficiency).

Options: Available in both small and large sizes

This innovative cold plate is compact, vibration-free, precise, economical, and easy to maintain and clean.

The temperature control system guarantees optimal cooling for sectioning histological blocks. Additionally, the plastic screen on the cold surface eliminates direct contact between the blocks and condensed water to prevent swelling—a first for histology cold plates.

The transparent lid keeps the paraffin blocks at the optimal sectioning temperature, while the plastic screen prevents moisture ingress in the paraffin block (and swelling of the tissue sample).

KEY BENEFITS

• Portable and lightweight (kg): 1.2

• Small footprint (cm): 21.4 x 15.7 x 12.3

• Cooling temperature range (˚C): -5 to +10

• Input voltage/frequency (v/Hz): 110-240/50-60

• Operating voltage: 12V (DC) 

• Noise emission (dB): <40

Options available: 6-Lane: 16-18g core needle biopsies, 4-Lane: 11-14g core needle biopsies

Say goodbye to bottles for core needle biopsies and hello to Lumea BxBoards. Medical personnel now place tissue samples on special hydrophilic formalin-soaked sponges within the BxBoards. This innovative technology preserves anatomic orientation, allowing for more precise localization of diseases.

BxBoards also enhance safety for medical assistants, physicians, and lab personnel by significantly reducing formaldehyde exposure.

Clinics and surgery centers using the BxBoard report an 83% reduction in containers and a 92.5% reduction in formalin per prostate case.

Enhance your lab and optimize your grossing station with Lumea’s AI-driven BxCamera, a reliable and affordable machine-learning tool used on over 2 million specimens that measures and documents specimens in seconds.

The BxCamera takes grossing to the next level, enabling labs to gross specimens in seconds with minimal handling. A laboratory technician places a specimen under the camera, which uses artificial intelligence to quickly and accurately measure the entire surface area of the tissue.

The FocalRing tool is designed to reduce scanning failures and rescans commonly associated with poor focal plane definition of small tissue biopsies and cytology samples. It comes embedded in a block, and lab personnel section it at the same thickness as the tissue or cell structure that will be associated with it. Once the FocalRing is deparaffinized on the slide, place the desired sample (produced at the same thickness) within the ring. The slide can then go through the standard processes to stain and digitize, with the FocalRing providing the plane of focus for whole slide scanning.

The BxAlign is a multifaceted tool designed to reduce rescans, like our FocalRing, and also serves as a proprietary fiducial for Lumea’s digital pathology software and artificial intelligence. By implementing this tool at the embedding station along with the specimen(s), the BxAlign ensures a clear area of focus for the scanner and an unaltered fiducial marker regardless of how many sections of tissue are taken from the paraffin block.

Lumea’s BxBoard Anti-Slip Platform holds a BxBoard steady and in place during a procedure. The platform makes it easier for surgeons and physicians to load the BxBoard with tissue, especially if they do not have an assistant or nurse to assist during the biopsy.

Lumea’s embedding tampers are designed and sized to apply even pressure to the full extent of the BxChip. The tamper base is aluminum, which can heat up quickly and is less likely to adhere to the back of the BxChip. The ergonomic handle fits nicely between the thumb and index finger interspace without fatiguing the user’s hand.